Can I get approved for a 400,000 home loan with a 600 credit score?

Yes...quite possibly!   The title of this post is a question that was entered as a search that found Mortgage Porter.  Someone could buy a $400,000 home with a 600 credit score if:

FHA Scenario Possibility

• No late payments or derogatory credit in the past 12 months.  FHA insured loans do not use credit scores.
• Base loan amount at FHA loan limit (assuming King, Snohomish or Pierce Counties):  $362,790.
• Just shy of 10% down or a minimum of 3% down plus closing costs with a 6% seller contribution.

With conforming, if the other qualifying factors (income, assets, employment, down payment) are strong, the borrower may still qualify for a mortgage. 

At the very least, if your credit score is 600 and you're considering buying a home, I suggest contacting a Mortgage Professional to have your personal scenario reviewed.  The higher your credit score, the better your rate may be for a mortgage and a qualified Mortgage Professional should be able to advise you on how to improve your credit rating.